Assessing the Impact of Urinary Calculi on Patients’ Quality of Life (Including Physical Symptoms, Psychosocial Distress, Healthcare Utilization, and Economic Burden)

Anwar Rashed Ahmed Ahmed *

Specialized Medical Care Hospital, UAE.

*Author to whom correspondence should be addressed.


Globally, both prostate and kidney stones are among the most prevalent and important health problems that affect men. There is no denying that such circumstances will have detrimental effects on patients’ possible dimensions of quality of life. Pain, urinary dysfunction, and discomfort are the main factors responsible for worsening the quality of life. This psychosocial stress, which includes anxiety, depression, and impaired social relationships, intensifies the patient's ordeal. Healthcare consumption patterns like routine and frequent medical visits, diagnostic procedures, and therapeutic interventions depict the enormous need for the healthcare systems and the patients. Furthermore, the economic consequences, including direct medical costs, indirect productivity losses and socioeconomic unbalance, point out that kidney stones have multiple effects. People with these conditions are highly prone to anxiety, depression, and emotional distress as a result of constant fear of the coming recurrence and progressive nature of the disease. Relationships may become strained and individuals may have to fight loneliness and weak self-esteem, adding to the load from the illness. During their journey in the healthcare system, patients with kidney stones go through the processes of diagnostic tests, therapeutic interventions, and follow-up consultations. Patterns of usage demonstrate the complexity of treating these conditions, justifying reasons for reconsidering provisions of healthcare resources, services, and patient-provider communication. The complex interaction between disease pathology, patient experience, and healthcare outcomes is the focus of this review, drawing upon the current literature to serve this purpose. It is necessary to know all the mechanisms in the body to help in the development of better clinical management strategies, and patient support interventions, and to reduce the socioeconomic implications of prostate and kidney stones. This review shall focus on the implications that people, particularly men, experience when dealing with conditions such as kidney and renal stones. It will deeply reflect on their quality of life and how it is negatively impacted by the burden of diseases during their lifetime.

Keywords: Kidney stones, renal stones, quality of life, benign prostate hyperplasia (BPH), psychosocial distress, economic burdens

How to Cite

Ahmed, A. R. A. (2024). Assessing the Impact of Urinary Calculi on Patients’ Quality of Life (Including Physical Symptoms, Psychosocial Distress, Healthcare Utilization, and Economic Burden). Asian Journal of Research and Reports in Urology, 7(1), 35–40. Retrieved from


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Nojaba L, Guzman N. Nephrolithiasis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2024 Mar 20]. Available:

Alelign T, Petros B. Kidney stone disease: An update on current concepts. Adv Urol. 2018 Feb 4;3068365.

Khan SR, Pearle MS, Robertson WG, Gambaro G, Canales BK, Doizi S, et al. Kidney stones. Nat Rev Dis Primer. 2016 Feb 25;2:16008.

Dawson CH, Tomson CR. Kidney stone disease: Pathophysiology, investigation and medical treatment. Clin Med. 2012 Oct;12(5):467–71.

Leslie SW, Sajjad H, Murphy PB. Renal calculi. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 [cited 2024 Mar 20]. Available:

Treatment options for kidney stones. In: [Internet] [Internet]. Institute for Quality and Efficiency in Health Care (IQWiG); 2019 [cited 2024 Mar 20]. Available:

Fontenelle LF, Sarti TD. Kidney Stones: Treatment and Prevention. Am Fam Physician. 2019 Apr 15;99(8):490–6.

Leader AJ, Queen DM. Prostatic calculous disease. J Urol. 1958 Aug 1;80(2):142–6.

Kirby RS, Lowe D, Bultitude MI, Shuttleworth KE. Intra-prostatic urinary reflux: An aetiological factor in abacterial prostatitis. Br J Urol. 1982 Dec;54(6):729–31.

Geramoutsos I, Gyftopoulos K, Perimenis P, Thanou V, Liagka D, Siamblis D, et al. Clinical correlation of prostatic lithiasis with chronic pelvic pain syndromes in young adults. Eur Urol. 2004 Mar;45(3):333–7;discussion 337-338.

Lotan Y. Economics and cost of care of stone disease. Adv Chronic Kidney Dis. 2009 Jan 1;16(1):5–10.

Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC. Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney Int. 2003 May;63(5):1817–23.

Borghi L, Schianchi T, Meschi T, Guerra A, Allegri F, Maggiore U, et al. Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med. 2002 Jan 10;346(2):77–84.

Miyaoka R, Ortiz-Alvarado O, Kriedberg C, Alanee S, Chotikawanich E, Monga M. Correlation between stress and kidney stone disease. J Endourol. 2012 May;26 (5):551–5.

Diniz DHMP, Schor N, Blay SL. Stressful life events and painful recurrent colic of renal lithiasis. J Urol. 2006 Dec;176(6 Pt 1):2483–7;discussion 2487.

Chung SD, Keller JJ, Lin HC. Increased risk of depressive disorder within 1 year after diagnosis with urinary calculi in Taiwan. Psychiatry Res. 2012 Jul 30;198 (2):332–3.

Diniz DHMP, Blay SL, Schor N. Quality of life of patients with nephrolithiasis and recurrent painful renal colic. Nephron Clin Pract. 2007;106(3):c91-97.

Penniston KL, Nakada SY. Development of an instrument to assess the health related quality of life of kidney stone formers. J Urol. 2013 Mar;189(3):921–30.

Penniston KL, Antonelli JA, Viprakasit DP, Averch TD, Sivalingam S, Sur RL, et al. Validation and reliability of the wisconsin stone quality of life questionnaire. J Urol. 2017 May;197(5):1280–8.

Raja A, Wood F, Joshi HB. The impact of urinary stone disease and their treatment on patients’ quality of life: A qualitative study. Urolithiasis. 2020;48(3):227–34.

Patel N, Brown RD, Sarkissian C, De S, Monga M. Quality of life and urolithiasis: The patient - reported outcomes measurement information system (PROMIS). Int Braz J Urol Off J Braz Soc Urol. 2017;43(5):880–6.

Angell J, Bryant M, Tu H, Goodman M, Pattaras J, Ogan K. Association of depression and urolithiasis. Urology. 2012 Mar;79(3):518–25.

Bryant M, Angell J, Tu H, Goodman M, Pattaras J, Ogan K. Health related quality of life for stone formers. J Urol. 2012 Aug;188(2):436–40.

Akram M, Jahrreiss V, Skolarikos A, Geraghty R, Tzelves L, Emilliani E, et al. Urological guidelines for kidney stones: Overview and comprehensive update. J Clin Med. 2024 Feb 16;13(4):1114.

Bhojani N, Bjazevic J, Wallace B, Lee L, Kaler KS, Dion M, et al. UPDATE – Canadian Urological Association guideline: Evaluation and medical management of kidney stones. Can Urol Assoc J. 2022 Jun;16(6):175–88.

Bensalah K, Tuncel A, Gupta A, Raman JD, Pearle MS, Lotan Y. Determinants of quality of life for patients with kidney stones. J Urol. 2008 Jun;179(6):2238–43;discussion 2243.

Donnally CJ, Gupta A, Bensalah K, Tuncel A, Raman J, Pearle MS, et al. Longitudinal evaluation of the SF-36 quality of life questionnaire in patients with kidney stones. Urol Res. 2011 Apr;39(2): 141–6.

Cella D, Riley W, Stone A, Rothrock N, Reeve B, Yount S, et al. The patient-reported outcomes measurement information system (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008. J Clin Epidemiol. 2010 Nov;63 (11):1179–94.

Harada K, Igari D, Tanahashi Y. Gray scale transrectal ultransonography of the prostate. J Clin Ultrasound JCU. 1979 Feb;7(1):45–9.

Jeon HJ, Chung HC, Song JM. Effects of residual prostatic calculi on lower urinary tract symptoms after transurethral resection of prostate. Korean J Urol. 2005 Jun;46(6): 569–73.