Paraneoplastic Chronic Inflammatory Demyelinating Polyradiculoneuropathy Associated with Renal Cell Carcinoma – A Rare but Critical Diagnosis
Published: 2024-10-31
Page: 88-91
Issue: 2024 - Volume 7 [Issue 1]
M K Manu
Department of Urology, Govt. Medical College, Thiruvananthapuram, India.
K Ram Mohan
Department of Medical Neurology, Govt. Medical College, Thiruvananthapuram, India.
Mohan Amal
*
Department of Urology, Govt. Medical College, Thiruvananthapuram, India.
C Lingesh Sairam
Department of Urology, Govt. Medical College, Thiruvananthapuram, India.
Harikrishnan AB
Department of Urology, Govt. Medical College, Thiruvananthapuram, India.
SJ Aquil Faris
Department of Urology, Govt. Medical College, Thiruvananthapuram, India.
*Author to whom correspondence should be addressed.
Abstract
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in the context of renal cell carcinoma (RCC) is a rare occurrence. A 73year old male presented with 6 months history of progressive weakness, was diagnosed as CIDP. His condition deteriorated despite treatment, leading to quadriplegia. Further evaluation with imaging revealed a left sided RCC. Following radical nephrectomy, the patient experienced substantial sensory and motor function improvement. This case highlights a rare paraneoplastic link between CIDP and RCC, emphasizing the importance of considering paraneoplastic syndromes in patients with atypical or treatment-resistant neurological conditions. Early recognition and management of the underlying malignancy can significantly improve neurological outcomes.
Keywords: Chronic inflammatory demyelinating polyradiculoneuropathy, renal cell carcinoma, paraneoplastic syndrome, Quadriplegia