Open Access Case Report

Abdominal Compartment Syndrome: A Rare but Fatal Complication of Percutaneous Nephrolithotomy

Sujeet Poudyal, Bipendra Dhoj Kulung Rai, Pawan Dhital, Manish Pradhan, Suman Chapagain, Bhoj Raj Luitel, Pawan Raj Chalise, Uttam Kumar Sharma, Prem Raj Gyawali

Asian Journal of Research and Reports in Urology, Page 1-5

Background: Percutaneous Nephrolithotomy (PCNL) is the standard of treatment for large renal stones. Intra-abdominal hypertension during PCNL due to extravasation of irrigation fluid in the peritoneal cavity may lead to organ dysfunction and may be fatal if not intervened on time.

Case Presentation: We report a case of abdominal compartment syndrome as a complication of PCNL. After a timely diagnosis, the case was managed successfully with percutaneous intraperitoneal drainage.

Conclusion: It is imperative to be aware of raised intra-abdominal pressure during PCNL to prevent abdominal compartment syndrome and to avoid its fatal outcome.

Open Access Original Research Article

Is Serum PSA a Predictor of Lower Urinary Tract Symptom Severity in Nigerian Males 40 Years and above?

Edoise M. Isiwele, Ima-Abasi E. Bassey, Eyam S. Eyam

Asian Journal of Research and Reports in Urology, Page 1-5

Background: Prostatic diseases are the commonest cause of lower urinary tract symptoms (LUTS) in men worldwide. The most ideal method for assessing symptom severity in men with LUTS currently is the International Prostate Symptom Score (IPSS). Prostate specific antigen (PSA) is widely in use as an indicator of prostatic disease in general. Few studies have been carried out to correlate PSA with symptom severity in men with LUTS.

Aim: To correlate Prostate Specific Antigen (PSA) values with International Prostate Symptom Scores (IPSS) in a screened population of male subjects 40 years and above presenting with symptoms at a medical outreach.

Study Design: Cross-sectional descriptive study.

Place and Time of Study: The study was carried out at the University of Calabar, South-Southern Nigeria in November 2016.

Methodology: Sixty one male subjects were interviewed using the IPSS questionnaire after which blood samples for PSA estimation were collected. PSA values were then correlated with IPSS and Quality of Life (QoL) scores.

Results: Sixty one male patients with mean age 52.03±7.5 years were included in the study. Over 67% of subjects had a PSA value less than 4ng/ml. No statistically significant correlation was found between PSA and IPSS scores or QoL values in the subjects.

Conclusion: This study shows PSA not to be a predictor of prostate symptom severity. More studies need to be carried out to be able to confirm these findings.

Open Access Original Research Article

Antibiotic Susceptibility Profile of Klebsiella Species Isolated from Pregnant Women with Dysuria Attending Selected Medical Centre in Northern Nigeria

M. Umar, I. A. Maidoki, A. A. Yaya, G. K. Ajiya, S. P. E. Jakheng, I. M. Abdulkarim, I. C. Amuta

Asian Journal of Research and Reports in Urology, Page 1-8

Background: Urinary Tract Infection (UTI) is caused by the presence and growth of microorganisms in the urinary tract. Klebsiella infection is perhaps one of the common bacterial infections of mankind capable of causing urinary tract infections.

Aims: This study targeted to evaluate the antibiotic susceptibility profile of Klebsiella species isolated from pregnant women reported with dysuria attending selected Medical Centre in Northern Nigeria.

Place and Duration of Study: The study was conducted at the Microbiology unit, Nigerian Institute of Leather and Science Technology, Zaria, and Ahmadu Bello University Health Service, Kaduna, Nigeria, between July 2010 and February 2011.

Methodology: Fifty mid-stream urine samples of were collected from consented pregnant women complaining of painful urination, attending selected medical centre in Northern Nigeria. Klebsiella species were isolated and biochemically characterized using standard microbiological methods. The isolates were subjected to antimicrobial sensitivity test using Kirby-Bauer disc diffusion technique.

Results: The prevalence of Klebsiella species was found to be 5 (10%). The klebsiellae species identified biochemically includes Klebsiella oxytoca and K. pneumoniae. The highest antimicrobial susceptibility in Klebsiella species was recorded by ciprofloxacin (100%) and gentamicin (100%). Resistance was recorded by ampicillin (0%). The antibiotics that were found to be more effective such as ciprofloxacin and gentamicin are regarded to be the first line drugs of choice for the treatment of urinary tract infections caused by the isolated Klebsiella species. Thus, continuous monitoring of antibacterial susceptibility before antibiotic prescription is important in order to monitor any emergence of resistance to the commonly active antimicrobials.

Conclusion: Klebsiella oxytoca and K. pneumoniae were isolated amongst the screened pregnant women with overall prevalence of 10%. From the results obtained, ciprofloxacin and gentamicin were found to be the first line drugs of choice for the treatment of urinary tract infections caused by the isolated klebsiellae species, whereas ampicillin recorded less activity.